{"id":32,"date":"2021-11-11T13:31:32","date_gmt":"2021-11-11T13:31:32","guid":{"rendered":"https:\/\/sanitura.bio.demokritos.gr\/?page_id=32"},"modified":"2021-11-11T13:34:32","modified_gmt":"2021-11-11T13:34:32","slug":"sanituragr","status":"publish","type":"page","link":"https:\/\/sanitura.bio.demokritos.gr\/","title":{"rendered":"SANITURA"},"content":{"rendered":"\n[et_pb_section fb_built=”1″ fullwidth=”on” _builder_version=”4.13.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_fullwidth_image src=”https:\/\/sanitura.bio.demokritos.gr\/wp-content\/uploads\/2021\/11\/Sanitura3.png” title_text=”Sanitura3″ _builder_version=”4.13.0″ _module_preset=”default” width=”50%” module_alignment=”center” global_colors_info=”{}”][\/et_pb_fullwidth_image][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.13.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_row _builder_version=”4.13.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.13.0″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.13.0″ _module_preset=”default” global_colors_info=”{}”]

SANITURA (\u03a0\u03a1\u039f\u03a3\u0394\u0399\u039f\u03a1\u0399\u03a3\u039c\u039f\u03a3 \u03a3\u03a4\u039f\u03a7\u03a9\u039d \u039a\u0391\u0399 \u0391\u039d\u0391\u03a0\u03a4\u03a5\u039e\u0397 \u039a\u0391\u0399\u039d\u039f\u03a4\u039f\u039c\u03a9\u039d \u03a0\u03a1\u039f\u03a3\u0395\u0393\u0393\u0399\u03a3\u0395\u03a9\u039d \u0393\u0399\u0391 \u0395\u03a6\u0391\u03a1\u039c\u039f\u0393\u0395\u03a3 \u03a3\u03a4\u0397\u039d \u03a5\u0393\u0395\u0399\u0391 \u039a\u0391\u0399 \u03a4\u039f \u03a0\u0395\u03a1\u0399\u0392\u0391\u039b\u039b\u039f\u039d)<\/span><\/strong><\/h1>[\/et_pb_text][et_pb_divider divider_weight=”3px” _builder_version=”4.13.0″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_divider][et_pb_text _builder_version=”4.13.0″ _module_preset=”default” global_colors_info=”{}”]

\u03a4\u03bf \u03ad\u03c1\u03b3\u03bf <\/span>SANITURA (<\/span>MIS 5002514) \u03b5\u03bd\u03c4\u03ac\u03c3\u03c3\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7 \u0394\u03c1\u03ac\u03c3\u03b7 \u03a3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ae\u03c2 \u0391\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2 \u0395\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 \u03a4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ce\u03bd \u03a6\u03bf\u03c1\u03ad\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c7\u03c1\u03b7\u03bc\u03b1\u03c4\u03bf\u03b4\u03bf\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf \u0395\u03c0\u03b9\u03c7\u03b5\u03b9\u03c1\u03b7\u03c3\u03b9\u03b1\u03ba\u03cc \u03a0\u03c1\u03cc\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1 \u00ab\u0391\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1, \u0395\u03c0\u03b9\u03c7\u03b5\u03b9\u03c1\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ba\u03b1\u03b9 \u039a\u03b1\u03b9\u03bd\u03bf\u03c4\u03bf\u03bc\u03af\u03b1\u00bb \u03c3\u03c4\u03bf \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf \u03c4\u03bf\u03c5 \u0395\u03a3\u03a0\u0391 2014-2020, \u03bc\u03b5 \u03c4\u03b7 \u03c3\u03c5\u03b3\u03c7\u03c1\u03b7\u03bc\u03b1\u03c4\u03bf\u03b4\u03cc\u03c4\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u0395\u03bb\u03bb\u03ac\u03b4\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u0395\u03c5\u03c1\u03c9\u03c0\u03b1\u03ca\u03ba\u03ae\u03c2 \u0388\u03bd\u03c9\u03c3\u03b7\u03c2 (\u0395\u03c5\u03c1\u03c9\u03c0\u03b1\u03ca\u03ba\u03cc \u03a4\u03b1\u03bc\u03b5\u03af\u03bf \u03a0\u03b5\u03c1\u03b9\u03c6\u03b5\u03c1\u03b5\u03b9\u03b1\u03ba\u03ae\u03c2 \u0391\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2). \u0391\u03bd\u03c4\u03b9\u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03cc \u03c4\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03b5\u03bd\u03af\u03c3\u03c7\u03c5\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ce\u03bd \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03bf\u03c4\u03ae\u03c4\u03c9\u03bd \u03c4\u03bf\u03c5 \u0399\u0392\u0395 \u03c3\u03c4\u03bf \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf \u03c4\u03b7\u03c2 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03b1\u03c1\u03b9\u03c3\u03c4\u03b5\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03bf\u03c0\u03bf\u03af\u03b5\u03c2 \u03b5\u03bd\u03c4\u03ac\u03c3\u03c3\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b9\u03c2 \u0395\u03b8\u03bd\u03b9\u03ba\u03ad\u03c2 \u0391\u03bd\u03b1\u03c0\u03c4\u03c5\u03be\u03b9\u03b1\u03ba\u03ad\u03c2 \u0394\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2, \u03cc\u03c0\u03c9\u03c2 \u03b7 \u03ba\u03b1\u03c4\u03b1\u03bd\u03cc\u03b7\u03c3\u03b7 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03ce\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03b9\u03ce\u03bd\/\u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03cc \u03b2\u03b9\u03bf\u03b4\u03b5\u03b9\u03ba\u03c4\u03ce\u03bd \u03ba\u03b1\u03b9 \u03bd\u03ad\u03c9\u03bd \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ce\u03bd \u03c3\u03c4\u03cc\u03c7\u03c9\u03bd, \u03b7 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03c0\u03c1\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b6\u03c9\u03ca\u03ba\u03ce\u03bd \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03b9\u03ce\u03bd, \u03b7 \u03b5\u03be\u03b5\u03cd\u03c1\u03b5\u03c3\u03b7 \u03b2\u03b9\u03bf\u03b4\u03c1\u03b1\u03c3\u03c4\u03b9\u03ba\u03ce\u03bd \u03bc\u03bf\u03c1\u03af\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c6\u03c5\u03c4\u03b9\u03ba\u03ce\u03bd \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03c9\u03bd \u03b3\u03b9\u03b1 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\u03a5\u03c0\u03bf\u03ad\u03c1\u03b3\u03bf\u03c5 \u03b5\u03ba\u03c0\u03b1\u03b9\u03b4\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc\u03c2 \u03bd\u03ad\u03c9\u03bd \u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03cc\u03bd\u03c9\u03bd, \u03b2\u03bf\u03b7\u03b8\u03ce\u03bd\u03c4\u03b1\u03c2 \u03c3\u03c4\u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b4\u03b9\u03b1\u03c1\u03c1\u03bf\u03ae\u03c2 \u03bd\u03ad\u03c9\u03bd \u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03cc\u03bd\u03c9\u03bd \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc, \u03b5\u03bd\u03ce \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ce\u03bd \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03bf\u03c4\u03ae\u03c4\u03c9\u03bd \u03b1\u03bd\u03b1\u03ba\u03bf\u03b9\u03bd\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c4\u03cc\u03c3\u03bf \u03c3\u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03ae \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1 \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf \u03b5\u03c5\u03c1\u03cd \u03ba\u03bf\u03b9\u03bd\u03cc.<\/span><\/p>[\/et_pb_text][et_pb_divider divider_weight=”3px” _builder_version=”4.13.0″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_divider][et_pb_text _builder_version=”4.13.0″ _module_preset=”default” global_colors_info=”{}”]

\u0394\u0397\u039c\u039f\u03a3\u0399\u0395\u03a5\u03a3\u0395\u0399\u03a3<\/strong><\/h1>[\/et_pb_text][et_pb_divider divider_weight=”3px” _builder_version=”4.13.0″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_divider][et_pb_text _builder_version=”4.13.0″ _module_preset=”default” global_colors_info=”{}”]

\u039f\u03b9 \u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03b5\u03c2 \u03b4\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03c3\u03b5\u03b9\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c0\u03c1\u03bf\u03ba\u03cd\u03c8\u03b5\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c5\u03c0\u03bf\u03c3\u03c4\u03ae\u03c1\u03b9\u03be\u03b7 \u03c4\u03bf\u03c5 \u03ad\u03c1\u03b3\u03bf\u03c5 <\/span>SANITURA:<\/span><\/p>\n

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  1. Valanti E.K., Chroni A. and Sanoudou D. The future of apolipoprotein E mimetic peptides in the prevention of cardiovascular disease. Opin. Lipidol.<\/em> 30, 326-341 (2019).<\/li>\n
  2. Dafnis I., Raftopoulou C., Mountaki C., Megalou E. Zannis V. I. and Chroni A. ApoE isoforms and carboxyl-terminal truncated apoE4 forms affect neuronal BACE1 levels and A\u03b2 production independently of their cholesterol efflux capacity. Biochem J.<\/em> 475, 1839-1859 (2018).<\/li>\n
  3. Dafnis I., Argyri L., and Chroni A. Amyloid-peptide \u03b2 42 enhances the oligomerization and neurotoxicity of apoE4: the C-terminal residues Leu279, Lys282 and Gln284 modulate the structural and functional properties of apoE4. Neuroscience<\/em> 394, 144-155 (2018). (\u0395\u03b9\u03ba\u03cc\u03bd\u03b1 \u03c4\u03bf\u03c5 \u03ac\u03c1\u03b8\u03c1\u03bf\u03c5 \u03b5\u03c0\u03b9\u03bb\u03ad\u03c7\u03b8\u03b7\u03ba\u03b5 \u03b3\u03b9\u03b1 \u03c4\u03bf \u03b5\u03be\u03ce\u03c6\u03c5\u03bb\u03bb\u03bf \u03c4\u03bf\u03c5 \u03c4\u03b5\u03cd\u03c7\u03bf\u03c5\u03c2)<\/li>\n
  4. Delimitsou A., F. Fostira, D. Kalfakakou, P. Apostolou, I. Konstantopoulou, C. Kroupis, A.G. Papavassiliou, Z. Kleibl, E. Stratikos, G.E. Voutsinas+<\/sup><\/strong>, D. Yannoukakos+<\/sup><\/strong> (2019) Functional characterization of CHEK2 variants in a Saccharomyces cerevisiae system, Human Mutation 40(5):631-648, +<\/sup><\/strong>equal authorship. (IF: 5.359)<\/li>\n
  5. Lesgidou, N., Eliopoulos, E., Goulielmos, G.N. and Vlassi, M. (2018) Insights on the alteration of functionality of a tyrosine kinase 2 variant: A molecular dynamics study. Bioinformatics<\/em><\/strong>, 34 (17), i781\u2013i786 ( https:\/\/doi.org\/10.1093\/bioinformatics\/bty556<\/a><\/span> )<\/li>\n
  6. Vlassi, M., Kyritsis, K. A., Vizirianakis, I. S., Giannakouros, T., Aivaliotis, M., Nikolakaki, E. (2019). Data on the expression of SRPK1a in mammals. Data in Brief, <\/em><\/strong>25 92019)\u00a0 104210: 1-6 ( https:\/\/doi.org\/10.1016\/j.dib.2019.104210<\/a><\/span>)<\/li>\n
  7. Apostolou-Karampelis, D.Polychronopoulos&Y.Almirantis. Introduction of \u2018Generalized Genomic Signatures\u2019 for the quantification of neighbor preferences leads to taxonomy- and functionality-based distinction among sequences. Scientific Reports<\/em> (2019). DOI:10.1038\/s41598-018-38157-3<\/li>\n
  8. Feng, M., Fei, S., Xia, J., Labropoulou, V., Swevers, L., and Sun, J. (2020). Antimicrobial peptides as potential antiviral factors in insect antiviral immune response. Front. Immunol. 11, 2020.<\/li>\n
  9. Biratsi et al., A highly conserved mechanism for the detoxification and assimilation of the toxic phytoproduct L\u2011azetidine\u20112\u2011carboxylic acid in Aspergillus nidulans. Scientific Reports<\/em> 2021, https:\/\/doi.org\/10.1038\/s41598-021-86622-3<\/a><\/span><\/li>\n
  10. Vayenos D., RomanosEm. G., Papageorgiou G. C., Stamatakis K. (2020) The freshwater cyanobacterium Synechococcus sp. PCC7942 under salt stress:\u00a0 A cell factory for sucrose and hydrogen production. Photosynth. 146(1-3): 235\u2013245<\/li>\n
  11. Sagnou, M., Mavroidi, B., Shegani, A.,\u00a0 Paravatou-Petsotas, M.,\u00a0 Raptopoulou, C.,\u00a0 Psycharis, V.,\u00a0 Pirmettis,\u00a0 I., Papadopoulos, M.,\u00a0 Maria Pelecanou. (2019). Remarkable brain penetration of cyclopentadienyl M(CO)3+ (M = 99mTc, Re) derivatives of benzothiazole and benzimidazole paves the way for their application as diagnostic, with Single Photon Emission Computed Tomography (SPECT), and therapeutic agents for Alzheimer’s disease.\u00a0 J. Med. Chem. 62, 2638-2650<\/li>\n
  12. Kazantzis K.T., Koutsonikoli K., Mavroidi B., Zachariadis M., Alexiou P., Pelecanou M., Politopoulos K., Alexandratou E., Sagnou M. (2020). Curcumin derivatives as photosensitizers in Photodynamic Therapy: photophysical properties and in vitro studies with prostate cancer cells. Photochem. Photobiol. Sci. 19, 193\u2013206<\/li>\n
  13. Matiadis, D., Mavroidi, B., Panagiotopoulou, A., Methenitis, C., Pelecanou, M., Sagnou, M. (2020). (E)-(1-(4-Ethoxycarbonylphenyl)-5-(3,4-dimethoxyphenyl)-3-(3,4-dimethoxystyryl)-2-pyrazoline: Synthesis, Characterization, DNA-Interaction, and Evaluation of Activity Against Drug-Resistant Cell Lines. Molbank, M1114<\/li>\n
  14. Sagnou, M., Mavroidi, B., Kaminari, A., Boukos, N., Pelecanou, M. (2020). Novel isatinthiosemicarbazone derivatives as potent inhibitors of \u03b2-amyloid peptide (\u0391\u03b2) aggregation and toxicity.\u00a0 \u00a0 ACS Chem. Neurosci. 11, 2266-2276<\/li>\n
  15. Mourtas, S., Mavroidi, B., Marazioti, A., Kannavou, M., Sagnou, M., Pelecanou, M., Antimisiaris, S.G. (2020). Liposomes Decorated with 2\u2011(4\u2032-Aminophenyl)benzothiazole Effectively Inhibit A\u03b21\u221242 Fibril Formation and Exhibit in Vitro Brain- Targeting Potential. Biomacromolecules, 21, 4685-4698<\/li>\n
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  34. Taning et al. (2018) Engineered Flock House Virus for Targeted Gene Suppression Through RNAi in Fruit Flies (Drosophila melanogaster) in Vitro and in Vivo. Front. Physiol. 9:805<\/li>\n<\/ol>[\/et_pb_text][et_pb_divider divider_weight=”3px” _builder_version=”4.13.0″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_divider][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n","protected":false},"excerpt":{"rendered":"

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